SUATU KAJIAN MOLEKULER KETERGANTUNGAN NIKOTIN

Agustina Setiawati

Abstract


Abstract: Nicotine, a simple chemical substance from tobacco, stimulates addiction byneuroadaptation inducing rewards system in human brain. Molecular mechanism of nicotineaddiction in rewards system are mediated by nicotinic acetylcholine receptor (nAChR) andactivate dopaminergic neuron. Thus, nicotine addiction are also induce other neurottransmitterand hormone release: norephinefrin, serotonin, opioid, glutamat and mono amine oxidase.

Keywords: nicotine, addiction, rewards system.


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DOI: https://doi.org/10.24071/jpsc.0098

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Copyright (c) 2016 Journal of Pharmaceutical Sciences and Community

 

 

 

 

 

 

 

   

Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community)

Published by Faculty of Pharmacy, Universitas Sanata Dharma Yogyakarta

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