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Email this article ASSOCIATION BETWEEN SMOKING BEHAVIOUR AND GLYCOHEMOGLOBINE LEVELS AMONG ADULT JAVANESE INDONESIAN SMOKERS
(1) Faculty of Pharmacy, Sanata Dharma University, Yogyakarta
(2) Faculty of Pharmacy, Sanata Dharma University, Yogyakarta
(*) Corresponding Author
Abstract
Nicotine, the active compound in cigarettes, can cause impaired glucose metabolism by
increasing insulin resistance as well as decreasing insulin secretion in ? cell pancreas. This
condition can increase the risk of type 2 diabetes in human. This study aims to evaluate the effect
of smoking behaviour, determined by Cigarette per Day (CPD) and smoking duration, on
glychohemoglobine (HbA1c) levels of Javanese Indonesian smokers. 30 smokers were studied
consisting of 7 smokers with <10 CPD, 19 smokers with 11-20 CPD and 4 smokers with 21-30
CPD. They had been smoking for more than 10 years. The whole blood sample was used to
examine the HbA1c levels. The HbA1c levels were tested at Bethesda Hospital's clinic
laboratories using Architect 600 instrument. The results showed that CPD and smoking duration
significantly influenced HbA1c, in which F count was > F table (370.541> 3.354) with
significance < 0.05 (2.35. 10-20 < 0.05) and multiple correlation coefficient (R) of 0.982.
Therefore, based on this research finding, it was concluded that longer smoking duration and
higher CPD caused higher smokers HbA1c level.
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DOI: https://doi.org/10.24071/jpsc.002408
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Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community)
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