SUATU KAJIAN MOLEKULER KETERGANTUNGAN NIKOTIN

Agustina Setiawati(1*),

(1) 
(*) Corresponding Author

Abstract


Abstract: Nicotine, a simple chemical substance from tobacco, stimulates addiction byneuroadaptation inducing rewards system in human brain. Molecular mechanism of nicotineaddiction in rewards system are mediated by nicotinic acetylcholine receptor (nAChR) andactivate dopaminergic neuron. Thus, nicotine addiction are also induce other neurottransmitterand hormone release: norephinefrin, serotonin, opioid, glutamat and mono amine oxidase.

Keywords: nicotine, addiction, rewards system.


Full Text:

PDF


DOI: https://doi.org/10.24071/jpsc.0098

Refbacks

  • There are currently no refbacks.


Copyright (c) 2016 Journal of Pharmaceutical Sciences and Community

 

 

 

 

 

 

 

  

Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community)

Published by Faculty of Pharmacy, Universitas Sanata Dharma Yogyakarta

Creative Commons Licence
This work is licensed under a Creative Commons Attribution 4.0 International License.