FORMULATION OF SUNSCREEN CREAM OF PARIJOTO FRUIT EXTRACT  (Medinilla speciosa Blume) AND IN VITRO SPF VALUE TEST

Elsa Tamara Geraldine; Ema Dwi Hastuti

doi:10.24071/jpsc.001525

FORMULATION OF SUNSCREEN CREAM OF PARIJOTO FRUIT EXTRACT (Medinilla speciosa Blume) AND IN VITRO SPF VALUE TEST

Elsa Tamara Geraldine⁽¹⁾, Ema Dwi Hastuti^(2*),

(1)
(2) STIKES Cendekia Utama Kudus
(*) Corresponding Author

Abstract

Sunscreen preparations are cosmetic preparations used as a protection to reduce the impact of sun exposure whose formulations contain active ingredients to absorb or diffuse sunlight, especially in areas of ultraviolet and infrared wave emissions. One of the potential natural ingredients for a sunscreen is parijoto fruit (Medinilla speciosa Blume). It contains flavonoid compounds that are able to prevent the harmful effects of UV rays. The objective of this research is to find out the formula of sunscreen cream of parijoto extract that meets the good physical quality of cream and to find out the result of SPF value test of parijoto fruit extract as sunscreen cream preparation in Vitro. The design of the study was experimental research conducted in the laboratory. The sample used in this research was parijoto made into thick extract by maceration method. Further, the viscous extract obtained was made to be a sunscreen cream and then tested either its physical evaluation or calculation of SPF value. The results of this study indicate that the preparation of sunscreen cream of parijoto fruit extract included in the extra protection category with the value is 6.66 and can be made into the good and stable preparations. The sunscreen cream of parijoto fruit extract has good physical properties and also has activity as UV protection in vitro.

Keywords

cream; parijoto fruit (Medinilla speciosa Blume); SPF; sunscreen

Full Text:

PDF

References

Arief, D.A., Sangi, M.S., and Kamu, V.S. 2017. Skrining Fitokimia dan Uji Toksisitas Ekstrak Biji Aren (Arenga pinnata MERR.). Jurnal MIPA UNSRAT, 6(2), 1215.

Artini, P.E.U.D., Astuti, K.W, Warditiani, N.K. 2008. Uji fitokimia ekstrak etil asetat rimpang bangle (Zingiber purpureum Roxb.). Jurnal Farmasi Udayana, 3, 17.

Chiari, B.G., Trovatti, E., Pecoraro, ., Corra, M. A., Cicarelli, R.M.B., Ribeiro, S.J.L., and Isaac, V.L.B. 2014. Synergistic effect of green coffee oil and synthetic sunscreen for health care application. Industrial Crops and Products, 52, 389393.

Gozali, D., Abdassah, M., Subghan, A., and Lathiefah, S.A. 2009. Formulasi Krim Pelembab Wajah yang Mengandung Tabir Surya Nanopartikel Zink Oksida Salut Silikon. Jurnal Farmaka, 7(1), 37-47.

Hastuti, E.D. 2016. Optimasi Formula Extracted cream Bunga Rosela (Hibiscus sabdariffa L.) dan Pengaruhnya Terhadap Proliferasi Sel Pre-Adiposa 3T3-L1. Tesis. Universitas Gadjah Mada: Yogyakarta.

Mailana, D., Nuryanti, N., and Harwoko, H. 2016. Formulasi Cream Preparation Antioksidan Ekstrak Etanolik Daun Alpukat (Persea americana Mill.). Acta Pharmaciae Indonesia, 4(01), 21-28.

Marliana, E., and Saleh, C. 2011. Uji Fitokimia dan Aktivitas Antibakteri Ekstrak Kasar Etanol, Fraksi n-Heksana, Etil Asetat dan Methanol dari Buah Labu Air (Lagenari siceraria (Molina) Standl). Jurnal Kimia Mulawarman, 8, 6369.

Mokodompit, A.N., Jaya Edy, H., and Wiyono, W. 2013. Penentuan Nilai Sun Protective Factor (SPF) Secara In Vitro Sunscreen cream Ekstrak Ethanol Kulit Alpukat. Pharmacon, 2(3), 23022493.

Rahmawanty, D., and Fadhillaturrahmah. 2014. Studi Aktivitas Tabir Surya Buah Limpasu (Baccaurea Lanceolata) Berdasarkan Penentuan Nilai Sun Protection Factor (SPF) Secara In Vitro. Jurnal Pharma Science, 1(1), 55-58.

Rauf, A., Suryaningsi, and Yasin, R.A. 2017. Uji Potensi Tabir Surya Ekstrak Kulit Buah Jeruk Nipis (Citrus aurantifolia) Secara In Vitro. JF FIK UINAM, 5(3), 38.

Rindiyantoko, E., and Hastuti, E.D. 2017. Formulasi dan Uji Stabilitas Fisik Cream preparation Yang Mengandung Medinilla speciosa fruit extract (Medinella speciosa). in: Prosiding HEFA, 196-202.

Rosniah, R., Rusli, R., and Fridayanti, A. 2016. Penentuan Nilai Sun Protection Factor Aktivitas Tabir Surya Ekstrak Etil Asetat Daun Miana (Coleus atropurpureus) Secara In Vitro. in: Proceeding of Mulawarman Pharmaceuticals Conferences, 3, 374-378.

Setyowati, H., Hanifah, H.Z., and Nugraheni, R.P. 2013. Krim Kulit Buah Durian (Durio zibethinus L.) Sebagai Obat Herbal Pengobatan Infeksi Jamur Candida albicans. Media Farmasi Indonesia, 8(2), 17.

Sharon, N., Anam, S., and Yuliet. 2013. Formulasi Krim Antioksidan Ekstrak Ethanol Bawang Hutan (Eleutherine palmifolia L., Merr). Natural Science: Journal of Science and Technology, 2(3), 111122.

Suryanto, E. 2012. Fitokimia Antioksidan. Surabaya: Penerbit Putra Media Nusantara.

Tussanti, I., Johan, A., and Kisdjamiatun. 2014. Sitotoksisitas in vitro ekstrak etanolik Medinilla speciosa fruit (Medinilla speciosa, reinw.ex bl.) terhadap sel kanker payudara T47D. Jurnal Gizi Indonesia, 2(2), 5358.

Voight, R. 1994. Buku Pelajaran Teknologi Farmasi. Yogyakarta: Universitas Gadjah Mada.

Wachidah, L.N. 2013. Uji Aktivitas Antioksidan Serta Penentuan Kandungan Fenolat dan Flavonoid Total dari Medinilla speciosa fruit (Medinilla speciosa Blume). Skripsi, UIN Syarif Hidayatullah Jakarta.

Wulandari, S.S., Runtuwene, M.R.J., and Wewengkang, D. S. 2017. Aktivitas Perlindungan Tabir Surya Secara In Vitro dan In Vivo dari Extracted cream Ethanol Daun Soyogik (Saurauia bracteosa DC). Pharmacon, 6(3), 147156.

Yuliani, S.H., Hartini, M., Stephanie, B.P., and Istyastono, E.P. 2016. Perbandingan Stabilitas Fisis Sediaan Nanoemulsi Minyak Biji Delima dengan Fase Minyak Long-chain Trygliseride dan Medium-chain Trygliseride. Traditional Medicine Journal, 21(2).

Zulkarnain, A.K., Marchaban, M., Wahyuono, S., and Susidarti, R. A. 2015. SPF In Vitro and the Physical Stability of O/W Cream Optimal Formula from the Partition Product of Mahkota Dewa (Phaleria macrocarpa (Scheff) Boerl). Indonesian Journal of Pharmacy, 26(4), 210218.

DOI: https://doi.org/10.24071/jpsc.001525