THE EFFECT OF NaOH CONCENTRATION IN DELIGNIFICATION PROCESS ON MICROCRYSTALLINE CELLULOSE FROM GREEN ALGAE (Cladophora sp.) AS THE RENEWABLE MARINE PRODUCT

I Gusti Ngurah Jemmy Anton Prasetia, Shelia Deviana, Trisna Damayanti, Angga Cahyadi, I Made Agus Gelgel Wirasuta

Abstract


Research on marine natural resources as an excipient material of pharmaceutical product is still rare. One of the marine products is the green algae, Cladophora sp. High cellulose content causes Cladophora sp. which can be used as an alternative material of microcrystalline cellulose (SM). There are two stages to produce SM, namely delignification and hydrolysis. Delignification is the process of removing the lignin of complex compounds. The delignification process is carried out chemically in alkaline situation using a NaOH solution which dissolves lignin, carbohydrates, organic acids, and resins so that cellulose is released from its bonds. This is important because the presence of lignin may inhibit acid penetration prior to hydrolysis. Therefore, the purpose of this study is to investigate the effect of delignification by using NaOH solution at various concentrations (2, 4, and 6%) to cellulose content and physical character of microcrystalline cellulose from Cladophora sp. (SMC). In the hydrolysis process, 5% HCl solution was used. SMCs of various concentrations of NaOH were observed and the cellulose levels included alpha, beta and gamma levels. While the physical character observation is done on Scanning Electron Microscopy (SEM) test. Based on the cellulose content, the higher the concentration of NaOH used, the higher the alpha cellulose will increase. The opposite result occurs on the measurement of beta and gamma cellulose. Based on SEM test, it appears that there is no effect of increasing NaOH concentration on physical character of SMC.


Keywords


Cladophora sp.; delignification; microcrystalline cellulose; NaOH; SEM

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References


Camacho, D.H., Gerongay, S.R.C., and Macalinao, J.P.C. 2013. Cladophora Cellulose-Polyaniline Composite for Remediation of Toxic Chromium (VI). Cellulose Chemistry and Technology, 47(1-2), 125-132.

Dewantara Putra, I.G.N., Prasetia, I.G.N., Aparigraha, G.A. 2016. Karakteristik MCC Jerami Padi Beras Merah Dengan Metode Delignifikasi NaOH 5%. Jurnal Farmasi Udayana. 5(1), 20-23.

Gunam, I.B.W., Ketut B., and I Made Y.S.G. 2010. Pengaruh Perlakuan Delignifikasi Dengan Larutan NaOH dan Konsentrasi Substrat Jerami Padi Terhadap Produksi Enzim Selulase Dari Aspergilus niger NRRL A-II, 264. Jurnal Biologi. 14(1), 55-61.

Mihranyan, A. 2011. The Cellulose From Cladophorales Green Algae: From Environmental Problem to High-Tech Composite Materials. Journal of Applied Polymer Science. 119, 2449-2460.

Prasetia, I G. N., Dewantara Putra, I.G.N., Arsana, D.A.M.I.P.S., dan Merlina Prabayanti, N.P. 2015. Studi Karakteristik Farmasetis Mikrokristalin Selulosa dari Jerami Padi Varietas Lokal Bali. Jurnal Sains Materi Indonesia, 17(3), 119-123.

Prasetia, I.G.N., and Dewantara Putra, I.G.N. 2015. Pengaruh Konsentrasi NaOH Terhadap Pembentukan Alfa Selulosa Pada Pembuatan Selulosa Mikrokristal Dari Jerami Padi Varietas IR64. Prosiding Seminar Nasional Sains dan Teknologi (Senastek) 2015. Bali: Universitas Udayana.

Standar Nasional Indonesia (SNI). 2009. Pulp-Cara Uji Kadar Selulosa Alfa, Beta, dan Gamma. Jakarta: Badan Standardisasi Indonesia.

Sumada, K., Tamara, P.E., and Alqani, F. 2011. Isolation Study of Efficient α-Cellulose From Waste Plant Stem Manihot Esculenta crantz. Jurnal Teknik Kimia. 5(2), 434-438.

Sze, P. 1993. A Biology of the Algae 2nd Ed. Iowa: Wm. C. Brown Publishers.




DOI: http://dx.doi.org/10.24071/jpsc.1521026

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Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community)

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